Brand Name | Status | Last Update |
---|---|---|
alendronate | ANDA | 2024-11-22 |
alendronate sodium | ANDA | 2025-02-19 |
binosto | New Drug Application | 2025-02-24 |
fosamax | New Drug Application | 2024-04-16 |
fosamax plus d | New Drug Application | 2024-04-17 |
Patent | Expires | Flag | FDA Information |
---|---|---|---|
Alendronate Sodium, Binosto, Radius | |||
9592195 | 2031-12-05 | DP |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Osteoporosis | D010024 | EFO_0003882 | M81.0 | 3 | — | 10 | 2 | 2 | 17 |
Postmenopausal osteoporosis | D015663 | EFO_0003854 | — | — | — | 6 | 2 | — | 8 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Bone diseases | D001847 | — | M89.9 | — | — | 1 | — | — | 1 |
Osteitis deformans | D010001 | EFO_0004261 | M88 | — | — | 1 | — | — | 1 |
Vitamin d deficiency | D014808 | EFO_0003762 | E55 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Esophageal neoplasms | D004938 | — | C15 | — | — | — | — | 1 | 1 |
Adenocarcinoma | D000230 | — | — | — | — | — | — | 1 | 1 |
Squamous cell carcinoma | D002294 | — | — | — | — | — | — | 1 | 1 |
Squamous cell neoplasms | D018307 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Alendronic acid |
INN | alendronic acid |
Description | Alendronic acid is a 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups. It has a role as an EC 2.5.1.1 (dimethylallyltranstransferase) inhibitor and a bone density conservation agent. It is a 1,1-bis(phosphonic acid) and a primary amino compound. It is a conjugate acid of an alendronate(1-). |
Classification | Small molecule |
Drug class | calcium metabolism regulators |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | NCCCC(O)(P(=O)(O)O)P(=O)(O)O |
PDB | — |
CAS-ID | 66376-36-1 |
RxCUI | — |
ChEMBL ID | CHEMBL870 |
ChEBI ID | 2567 |
PubChem CID | 2088 |
DrugBank | DB00630 |
UNII ID | X1J18R4W8P (ChemIDplus, GSRS) |